Programme
All talks will be held in The Jacqueline du Pré Music Building (JdP). Any changes to the programme will be notified on this page as soon as possible.
16 March
4.30pm-7.00pm Registration, JdP Foyer
7.30pm-9.00pm Dinner, College Dining Hall (By prior booking/invitation only)
17 March
8.00am-8.50am Registration, JdP Foyer
8.50am Welcome by Dr Muhammad Sohail
Session 1: Chair Professor Andy Miller
9.00am Dr Erik Miska, University of Cambridge, UK
The complex life of small RNAs
9.30pm Professor Dr Georg Sczakiel, University of Lübeck, Germany
Cell stress-induced translocation of human Argonaute 2 protein is related to decreased RNA interference
10.00am Dr Stephanie Urschel, Thermo Scientific Genomics
A workflow for studying miRNA expression and identifying miRNA targets
10.30am Refreshment Break, Exhibitions and Posters
11.15am Dr Charles Lawrie, University of Oxford, UK
MicroRNA expression in lymphoma
11.45am Dr Brian Schyth, Technical University of Denmark, Denmark
In vivo screening of backbone-modified siRNAs for their ability to induce interferone-based off-target effects
12.15pm Dr Jörg Vollmer, Pfizer-Coley, Germany
Novel ways to modify immune modulation by DNA and RNA therapeutics
12.45pm Dr
Cecilia Lundin (Sponsored by PerkinElmer), University of Oxford, UK
RNAi screens to determine homologous recombination networks
1.00pm Lunch Break, Exhibitions and Posters
Session 2: Chair Dr Jörg Vollmer
2.30pm Dr Dmitry Samarsky, RXi Pharmaceuticals, USA
Combination of oligo configuration and chemical modification provides drug-like properties to RNAi molecules
3.00pm Dr Attila Seyhan, Pfizer-Wyeth, USA
Whole-genome RNAi screens to identify novel modulators of breast cancer genes
3.30pm Dr William Arthur, Merck & Co, Inc, USA
Identification of new regulators of the Wnt-ß-catenin pathway via RNAi screening
4.00pm Dr Tobias Poehlmann, Friedrich-Schiller-Universität Jena, Germany
Development of small interfering RNA, selectively activated in target cells
4.15pm Refreshment Break, Exhibitions and Posters
Session 3: Chair Dr Dmitry Samarsky
5.00pm Dr Glen Reid, University of Sydney, Australia
A rapid and sensitive method to detect siRNA-mediated mRNA cleavage in vivo using 5' RACE and a molecular beacon probe
5.15pm Dr Luc JW van der Laan, Erasmus MC-University Medical Center, The Netherlands
Cell-to-cell transmission of small RNAs extends the therapeutic reach of RNAi
5.30pm Ms Mariam Sharaf, Duke University, USA
Boranophosphate-modified RNA as potential anti-cancer therapeutic: Aptamers and RNA interference
5.45pm Ms Dana Danielson, Steacie Institute of Molecular Sciences, Canada
Modifying p19 viral suppressors of RNA Silencing: Developing FRET-based probes for detecting and quantifying protein-small RNA interactions
6.00pm Dr Sandra Laufer, University of Lübeck, Germany
Mechanistic studies of siRNA-mediated RNA interference in HeLa cell extract
6.15pm close of Day 1
7.45pm Dinner, College Dining Hall (By prior booking/invitation only)
18 March
Session 4: Chair Dr Erik Miska
9.00am Dr Petr Svoboda, Institute of Molecular Genetics, Czech Republic
Useless microRNAs in mammalian oocytes
9.30am Dr Martin Fabani, University of Cambridge, UK
Evaluation of peptide nucleic acids for in vivo inhibition of microRNA-155
10.00am Dr Jens Kurreck, University of Stüttgart, Germany
RNA interference approaches to inhibit cardiotropic viruses
10.30am Refreshment Break, Exhibitions and Posters
11.15am Dr Graeme Doran, Massachusetts Institute of Technology, USA
Modular elements modulating RNA stability
Session 5: Chair Professor Dr Georg Sczakiel
11.45am Dr Zdravka Medarova, Massachussetts General Hospital, USA
Image-guided siRNA delivery
12.15am Dr Patrick Lu, Sirnaomics, Inc, USA
Multi-targeted siRNA therapeutics with three generations of nanoparticle delivery
12.45pm Lunch Break, Exhibitions and Posters
2.30pm Dr Roger Adami, MDRNA, Inc, USA
A novel amino acid based delivery platform for therapeutic applications in bladder cancer and hepatocellular carcinoma
3.00pm Professor Andy Miller, Imperial College London, UK
Designing safe, self-assembly nanoparticles that enable nucleic acid therapeutics, molecular imaging and theranostics
3.30pm Dr Seyed Javad Mowla, Tarbiat Modares University, Iran
Induction of apoptosis in tumour cell lines by suppressing the expression of OCT4B1 - a novel spliced variant of OCT4
4.00pm Refreshments
4.30pm Close of conference
