Conference Agenda & Speakers
Day-1: 19 March 2013
1.45pm-2.45pm: Registration and Coffee
2.50pm: Welcome and Housekeeping Announcements
Session 1: Chair Professor Dr Georg Sczakiel
3.00pm: Professor Kaz Taira, Japan
Special Guest Speaker
Title: Identification of functional genes by ribozyme and shRNA libraries
Professor, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba; The University of Tokyo; Tokyo University & Graduate School of Social Welfare; and Nagase & Co Ltd, Tokyo, Japan
3.40pm: Dr Annaleen Vermeulen, USA
Title: Optimized PCR conditions and increased shRNA fold representation improve reproducibility of pooled shRNA screens
Senior Scientist/R&D Manager, Thermo Fisher Scientific, USA
4.10pm: Refreshment Break, Exhibitions and Poster Viewing
5.00pm: Professor Dr Georg Sczakiel, Germany
Title: Evidence suggesting involvement of target RNA in guide strand-loading of active Argonaute-2
Professor and Director, Institute of Molecular Medicine, University of Luebeck, Germany
5.30pm: Dr Michael Hannus, Germany
Title: Defined, complex siRNA pools eliminate off-target effects
CSO, Intana Bioscience GmbH, Germany
6.00pm: Professor Achim Aigner, Germany
Title: RNAi, miRNA replacement or U1i: Various approaches for the knockdown of the oncogene Pim-1
Professor, Rudolf-Boehm-Institute for Pharmacology and Toxicology Clinical Pharmacology, University of Leipzig, Germany
6.30pm: Close of Day-1
7.15pm: Dinner (By Invitation only)
Day-2: 20 March 2013
Session 2: Chair Professor Dr Aichim Aigner
9.00am: Dr Negar Babae, The Netherlands
Title: Identification of novel anti-angiogenic miRNAs and their therapeutic potential
Postdoctoral Scientist, Schiffelers Laboratory, UMC Utrecht, The Netherlands
9.30am: Dr Dave Carter, UK
Title: Identification of a miRNA inducing cisplatin drug resistance in ovarian cancer
Senior Lecturer in Biomedcial Sciences, Department of Biological and Medical Sciences - Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, UK
10.00am: Professor Paul Holvoet, Belgium
Title: MicroRNAs and mitochondrial stress in obesity
Professor and Head, Atherosclerosis and Metabolism Unit, University of Leuven, Belgium
10.30am: Refreshment Break, Exhibitions and Poster Viewing
11.30am: Dr Paul Diehl, USA
Title: Pooled RNAi genetic screening to identify critical functional genes and novel drug targets
Director of Business Development, Cellecta, CA, USA
12.00am: Dr Steven Thompson, UK
Title: TBA
Sigma-Aldrich, UK
12.30pm: Lunch Break, Technology Workshops and Exhibitions
Technology Workshops
1.15pm-2.00pm: Sigma-Aldrich
2.10pm-2.20pm: Carl Zeiss
Session 3: Chair TBA
2.30pm: Dr Klaus Giese, Germany
Title: Development of liposomally-formulated siRNA for RNAi-based therapy: Atu027 for therapeutic application in oncology
CSO, Silence Therapeutics, Berlin, Germany
3.00pm: Professor Gilles Divita, France
Title: Peptide-based nanoparticles for targeted delivery of siRNA
Professor, Macromolecular Biochemistry Research Centre, CNRS-UMR, France
3.30pm: Dr Raymond Schiffelers, The Netherlands
Title: Intravenous delivery of novel anti-angiogenic miRNAs
Associate Professor, UMC Utrecht, The Netherlands
4.00pm: Refreshment Break, Exhibitions and Poster Viewing
4.40pm: Dr Mike Gait, UK
Keynote Speaker
Title: Inhibition of microRNAs by PNA and LNA-based oligonucleotides
MRC Laboratory of Molecular Biology, Cambridge, UK
5.20pm: Dr Dmitry Samarsky, PR China
Title: RNAi and antisense oligonucleotide in vivo delivery for therapeutic applications
EVP, Technology & Business Development, RiboBio, PR China
5.50pm: Professor Andrew Miller, UK
Title: Old wine in new bottles" - constant innovation in delivery system design is essential to improve functional delivery of RNAi effectors
Professor of Biochemistry, Kings College London, UK
6.20pm: Close of Day-1
7.15pm: Social Dinner (By invitation or prior booking only)
Day-3: 21 March 2013
Session 4: Chair Dr Mike Gait
9.00am: Dr Patrick Lu, USA
Title: The Prophylactic and Therapeutic Potentials of siRNA Inhibitors for Fighting Emerging Respiratory Viral Infections
CEO, Siranomics, USA
9.30am: Professor Jens Kurreck, Germany
Title: RNAi-based combination therapies against viruses
Professor of Biochemistry, Technical University Berlin, Berlin, Germany
10.00am: Dr Susanna Obad, Denmark
Title: Silencing of miR-122 for treatment of Hepatitis C
Drug Discovery Manager, Santaris Pharma, Denmark
10.30am: Refreshment Break, Exhibitions and Poster Viewing
11.00am: Dr Jonathan Watts, UK
Title: Increased binding affinity by fluorinated oligonucleotides: origins and implications
Lecturer in Chemical Biology, University of Southampton, UK
11.30am: Dr Kathia Zaleta-Rivera, USA
Title: Oligonucleotide therapeutic approaches for allele silencing of hMYL2-47K and hMYH7-403Q mutations in Hypertrophic Cardiomyopathy
Postdoctoral Research Scientist, Ashley Laboratory, Falk Cardiovascular Research Center, Stanford University School of Medicine, CA, USA
12.00am: Dr Tom Roberts, UK
Title: Investigation of extracellular microRNAs in the mdx mouse
Postdoctoral Research Scientists, Wood Laboratory, Department of Physiology, Anatomy and Genetics, University of Oxford, UK
12.30pm-1.15pm: Lunch, Networking and Close of Conference
