• Aptamers 2017
    4th Oxford Symposium on Aptamers
    11-12 April 2017
    St Hilda's College, Oxford, UK

    Co-hosted with our 3rd Therapeutic and Antisense Oligonucleotides Symposium, Oligo 2017 on 10 April at St Hilda's College, Oxford, UK
  • Aptamers 2017
    4th Oxford Symposium on Aptamers
    11-12 April 2017
    St Hilda's College, Oxford, UK

    Co-hosted with our 3rd Therapeutic and Antisense Oligonucleotides Symposium, Oligo 2017 on 10 April at St Hilda's College, Oxford, UK

Speakers & Agenda

(Subject to change)

All talks will be held in the Edward Boyle Auditorium, JdP, St Hilda’s College.

DAY 1 – 11th April

0800: Registration

0830: Housekeeping

0840: Welcome by the Symposium Chair

0850: Welcome by the INSOAP President

Session 1 – Chemical Modifications


Professor Jesper Wengel
Professor and Center Director
, BioNEC – A VKR Center of Excellence, FKF – University of Southern Denmark, Odense, Denmark

Title: Novel aptamers based on LNA and UNA


Dr Xianbin Yang
Director of R&D
, AM Biotechnologies, Houston, TX, USA

Title: X-Aptamers – Chemically modified aptamers that can be used for biomarker discovery


Dr Daniel Schneider
Senior Director
, Technology Development, Boulder, CO, SomaLogic, USA

Title: Next Generation Aptamers:  Enhancing Chemical Diversity with Multiple Pyrimidine Modifications


Professor Tom Brown
Professor of Chemistry
, Chemistry Research Laboratory, Department of Chemistry, University of Oxford, UK

Title: Chemical modification of aptamers

1040: Refreshments, exhibition, posters

 Session 2 – Diseases


Dr Gregory Penner
President & Founder
, NeoNeuro SAS, 38 Rue de Berri, Paris, France

Title: Development of aptamers for the treatment and diagnosis of Alzheimer’s disease


Professor Dr Ulrich Hahn (Symposium Chair)
University of Hamburg, Department Chemistry, Institute for Biochemistry and Molecular Biology, Hamburg, Germany

Title: Selectin and Integrin Aptamers


Professor Yoshikazu Nakamura
CEO & President, Ribomic Inc, Japan

Title: Anti-FGF2 aptamer restores bone growth affected in Achondroplasia transgenic mice


Professor Fernando Pastor
Principal Investigator
, Foundation for Applied Medical Research, Pamplona, Spain

Title: Targeting Co-Stimulation with Bi-Specific Aptamers to Melanoma Cancer Stem Cells

1300: Lunch, exhibition, posters


Dr Sarah Shigdar
Senior Lecturer in Medicine, Schoool of Medicine, Deakin University, Waurn Ponds, Australia

Title: Treating brain metastases with a bifunctional aptamer

Session 3 – Analysis/Diagnostics


Professor Anthony Cass
Professor of Chemical Biology
, Department of Chemistry, Institute of Biomedical Engineering, Imperial College London, UK

Title: Aptamers in Bioanalysis: from Lateral Flow to Nanopore Sensing


Dr Julian Tanner
Associate Professor & Coordinator
of Education Division of Biochemistry, University of Hong Kong, PR China

Title: Aptamers for Malaria Diagnosis


Professor Victoria Calzada
Principal Investigator,
Área de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la República, Montevideo-Uruguay

Title: Aptamers as molecular probes: multimodal imaging

1550: Refreshments, exhibition, posters

Session 4 – Tools/selection/design (Part I)


Dr David Bunka
Chief Technical Officer,
 Aptamer group, Bio Centre, Innovation Way, Heslington, York, UK

Title: Aptabind; Enabling Protein Purification


Dr Duncan Borthwick
Staff Scientist,
Dynamic Biosensors GmbH, Lochhamer Str 15, Planegg, Germany

Title: A Regenerating Biochip, Modelling the Kinetics of Aptamer Interactions using switchSENSE® Technology


Dr Sean Dembowski
Department of Chemistry, University of Minnesota–Twin Cities, 207 Pleasant St. SE, Minneapolis, MN, USA

Title: Isolating aptamers for membrane proteins using capillary electophoresis-SELEX

1740: Close of Day 1

1745: INSOAP AGM (open to all attendees)

1815: Aptamers Board meeting (Aptamers editorial board members only)

1915: Networking dinner (by prior booking or invitation only)

DAY 2 – 12th April

Session 4 – Tools/selection/design (Part II)


Dr Terry Steele
Assistant Professor, School of Materials Science & Engineering, College of Engineering, Nanyang Technological University, Singapore

Title: Exploiting aptamer adaptive binding towards reversible aptasensors


Dr Meltem Avci-Adali
University Hospital Tuebingen, Dept of Thoracic and Cardiovascular Surgery, University Hospital Tübingen, Tübingen, Germany

Title: Biofunctionalization of hydrogels with aptamers for tissue engineering applications


Professor Philip Johnson
Associate Professor
, Department of Chemistry, York University, Toronto, ON, M3J 1P3, Canada

Title: Two-Site Binding by the Cocaine-Binding Aptamer

Session 5 – Riboswitches


Professor Dr Beatrix Suess (Aptamers 2016 Chair)
Professor of Synthetic Biology, Technical University of Darmstadt, Germany

Title: Development of novel engineered riboswitches

1030: Refreshments, exhibition, posters


Dr Florian Groher
Department of Biology, Technical University Darmstadt, Schnittspahnstr 10, Darmstadt, Germany

Title: In Vivo Screening For New Synthetic Riboswitches


Dr Carlos Penedo
Principal Investigator
, Laboratory for Biophysics and Biomolecular Dynamics, SUPA School of Physics and Astronomy, University of St. Andrews, St Andrews, United Kingdom

Title: Single-molecule FRET structural analysis of nascent aptamer-expression platform riboswitch sequences along their transcriptional pathway


Professor Dr Mario Mörl 
Biochemistry and Molecular Biology, Institute for Biochemistry, Leipzig University, Brüderstr 34, Leipzig, Germany

Title: From Plug & Pray to Plug & Play – Aptamer-based transcriptional Riboswitches

1220: Lunch, exhibition, posters

Session 6 – Computation


Dr Muslum Ilgu
Aptalogic Inc, Molecular Biology Building, Ames, Iowa, USA

Title: Evaluation of MC-SYM structural predictions for an RNA aptamer with additional base stacking calculations and fluorescence of 2AP-substituted aptamers


Dr Gregory Penner
President & CEO, NeoVentures Biotechnology Inc, 5 York St, London, Ontario, N6A 1A1, Canada

Title: Using next generation sequence analysis to understand aptamer selection and application


Dr Maureen McKeague
Department of Health Sciences and Technology, ETH Zürich, Schmelzbergstrasse 9, Zürich, Switzerland

Title: Computational approaches for improving aptamers and their application to metabolic engineering

1420: Discussion Closing remarks by Professor Dr Ulrich Hahn

1440: Close and departure