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Aptamers
Open-access, peer-reviewed
The Eur J Extracellular Vesicles
Open-access, peer-reviewed

Waters – Digital Stand

From the everyday consumer to scientists in the laboratory, we all rely on accurate information to make critical decisions. Waters Corporation is the world’s leading specialty measurement company focused on improving human health and well-being through the application of high-value analytical technologies and industry leading scientific expertise.

Our decisions and actions are guided by two simple words – Deliver Benefit. Our founder, Jim Waters, coined these words to encapsulate the idea that we should positively impact our customers, employees, shareholders and society at every opportunity.

Driven by that ethos for over sixty years, Waters has continually pioneered chromatography, mass spectrometry and thermal analysis innovations. Whether it’s discovering new pharmaceuticals, assuring the safety of the world’s food and water supplies, or ensuring the integrity of a chemical entity in production, we are constantly working with our 40,000+ customers to change the world.

Waters solutions can help you to obtain superior analytical data for oligonucleotides and aptamers, from routine mass and sequence confirmation to more detailed impurity profiling

By combining ACQUITY UPLC instrument technology, industry leading Oligo Separation Technology (OST) columns, pre-validated MassPrep OST reference standard and a range of Mass Spectrometry systems, Waters brings an unrivalled level of performance for oligonucleotide, peptide and aptamer analysis.



The BioAccord is an integrated LC-MS system that greatly simplifies high-performance biopharmaceutical analysis. It’s easy-to-use and puts the decision making directly in your hands.

The BioAccord System is a self-calibrating, self-optimizing, self-sufficient tool that delivers high-quality data to help you tackle the challenges you face during biopharmaceutical development

Ideally suited to nucleotide and peptide analysis, now you can generate the data you need to make decisions without the need to be an expert mass spectrometrist.

 


Waters Oligonucleotide (OST) and Peptide (PST) Separation Technology columns contain second- generation hybrid silica BEH Technology particles functionalised with C18.

OST columns allow the separation of synthetic oligonucleotide samples, based on the well-established method of ion-pair, reversed-phase chromatography.

PST columns provide a consistent set of chromatographic tools across all research and development applications that require analysis and isolation of peptides.

Waters OST and PST columns deliver exceptional sample resolution and superior column life, making them the ideal choice for your application. Our manufacturing and QC testing procedures help ensure consistent batch-to-batch and column-to-column performance regardless of application demands.


Waters offer a wide range of advanced characterisation solutions for aptamers:

Xevo G2-XS QTof – high-resolution MS with enhanced sensitivity for in-depth characterization, including ms/ms sequence confirmation

Vion IMS QTof – The risk of not seeing everything in your sample can be high, especially if this results in incorrect identifications or time-consuming confirmatory experiments. Vion reduces this risk, making ion mobility quantitative and routinely usable

SYNAPT XS – for further characterisation of aptamers and associated impurities. Combining ion mobility measurements and separations with QTof MS enables analysis of aptamers by size and shape, as well as mass, to deliver increased selectivity and sensitivity beyond conventional MS.



Meet the Team – Waters Biopharma Specialists

Waters Biopharma Specialists cover a range of applications including oligonucleotides, peptides, characterisation of complex biotherapeutics, cell and gene therapies, bioseparations, protein glycosylation and biopharmaceutical development and manufacture.

Nick Pittman

Nick has worked with Waters for 7 years, looking after Chromatography and Mass Spec technologies across a range of applications including Pharmaceuticals, Health Sciences (Omics), Clinical Diagnostics and Food.  Previous to joining Waters, Nick spent 10 years working with LC and LC-MS in pharmaceutical development at Pfizer.

 

Dan Trenzinger

Dan has worked with Waters for 12 years, looking after chemistry technologies across a range of applications, including pharma, clinical, environmental, food and chemical analysis Previous to joining Waters, Dan spent 12 years working with LC in pharmaceutical development in the CRO industry.

Contact us:

To discuss your aptamer separation and characterisation requirements, please contact us on nick_pittman@waters.com or Daniel_trenzinger@waters.com.

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Important Deadlines

Early Registration: 17 Jul 2020
Standard Registration: 28 Aug 2020
Oral Abstracts: Closed
Poster Abstracts: 14 Aug 2020
Digital Posters: 28 Aug 2020

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