(Subject to change: The conference may finish slightly earlier or later than the advertised time)
All times mentioned refer to British Standard/Summer Time (BST) – London/GMT+01:00. Registered delegates will be sent joining information a few days before the conference.
World Time Converter: https://www.worldtimebuddy.com/
Presentation language: English
Venue: Edward Boyle Auditorium, The Jacqueline du Pré Music Building (JdP), St Hilda’s College, Oxford
0900: Registration and refreshments
0940: Housekeeping
0945: Welcome by Dr Nebojsa Janjic
0950: INSOAP/Aptamers updates by Professor Sarah Shigdar
Session 1 (Virtual): Chair Professor Sarah Shigdar
1000: Dr Katelyn Richards
Research Scientist, WearOptimo, Woolloongabba, Queensland, Australia
Rational maturation and library design for the development of Troponin-binding aptamers for in vivo biosensing applications
1020: Dr Hiroko Miki
Research Scientist, Corporate Research & Development Center, Toshiba Corporation, Kanagawa, Japan
Maximizing the Immobilized Amount of DNA Aptamer Probes on Graphene Odor Sensors
1040: Mr Lin Wang
Graduate Research Student, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Self-Assembly of DNA Tiles with G-quadruplex DNAzyme Catalytic Activity for Sensing Applications
1100: Dr Marimuthu Citartan
Senior Lecturer, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang, 13200 Malaysia
Secura-3 RNA aptamer as a promising molecular recognition element against the global transcription factor Human Pituitary Tumour Transforming Gene 1 (PTTG1)
1120: Miss Safiye Jafari
Graduate Research Student, Department of Health Sciences and Technology, ETH Zürich, Schmelzbergstrasse 9, 8092 Zürich, Switzerland
Development of electrochemical aptasensor for detection of aflatoxin B1 in cereals
1140: Miss Mengping Liu
Graduate Research Student, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Evolution of BMP-2-specific DNA aptamers for promoting BMP-2-induced osteogenesis in ECM mimetic scaffolds
1200: Professor Ajda Çoker-Gürkan
Professor, Department of Molecular Biology and Genetics, Biruni University, Topkapı, Istanbul, Turkey
X-aptamers against Growth Hormone Releasing Hormone (1-29) induces apoptosis via autophagy and endoplasmic reticulum stress in MiaPaca-2 and HT-29 cancer cells
1220: Miss Krisztina Percze
Graduate Research Student, Department of Molecular Biology, Semmelweis University, Budapest, Hungary
Tryptophan-like side chain holding aptamers inhibit RSV infection
1240-1310: Flash-talks-I
Presenters: Cao, Coombes, Guzdek, Kerler, Legen, Nakhjavani, Puchala, Samokhvalov, Singh, Sramkova, Svehlova, Tungsirisurp, Volek
1310: Lunch and networking at St Hilda’s College
Session 2 (virtual/in-person): Chair Dr Nebojsa Janjic
1400: Dr Robert Batchelor
Head of Biosensors Group, Nutromics Pty Ltd, Brunswick, Victoria, Australia
Electrochemical aptamer-based sensors: a platform technology supporting seconds-resolved, real-time molecular monitoring in the living body
1420: Dr Nebojsa Janjic
Chief Science Officer, SomaLogic Inc, Boulder, CO, USA
Aptamer-based analysis of plasma proteome of growing tumors
1440: Professor Philip Johnson
Professor of Chemistry, Department of Chemistry, York University, Toronto, Ontario, Canada
Structure-Function Studies of Aptamer-Small Molecule Complexes
1500: Professor Larry Gold (Keynote Speaker) (V)
Professor of Molecular Cellular & Developmental Biology, SomaLogic Inc, and College of Arts and Sciences, University of Colorado Boulder, Boulder, CO, USA
Broad Proteomics and Target Identification for Pain Therapeutics: Making the Leap from Correlation to Causality
1530: Coffee and networking at St Hilda’s College
Session 3: (Virtual): Chair Professor McKeague
1600: Professor Anna Marie Pyle
Sterling Professor of Molecular, Cellular and Developmental Biology and Department of Chemistry; Investigator, Howard Hughes Medical Institute; Yale University, New Haven, CT, USA
A Modified DNA Aptamer Mimics Viral RNA Utilizing a Unique Molecular Recognition Strategy with a Highly Unusual Structure
1620: Professor Bruce Sullenger
Dorothy W Beard Distinguished Professor of Experimental Surgery, Duke University, Durham, North Carolina, USA
Recanalization of Canine Large Vessel Occlusion 6 Hours Post Stroke by and IND Enabling Studies for VWF Aptamer DTRI-031
1640: Dr Gregory Penner
President & CEO, NeoVentures Biotechnology Inc, London, Canada & President & Founder, NeoNeuro SAS, Paris, France
Neomers, a novel approach to aptamer selection
1700: Ms Micaela Belleperche
Graduate Research Student, Department of Chemistry, McGill University
Montreal, Quebec, Canada
Fluorescent detection of 8-Oxoguanine using a structure-switching aptamer
1720-1750: Flash-talks-II
Presenters: Berman/Hertz, Chao, Choukeife, Churcher, Esmaeili, Kaiyum, LeDortz, Lewis, Martinez-Liu, Osborne, Mitchell, Schellinck, Shoara, Torres-Vazquez, Toscano
1900: Networking dinner
1000: Welcome
Session 4 (virtual/in-person): Chair TBA
1010: Professor Dr Beatrix Suess (V)
Professor, Synthetic Genetic Circuits, Technical University of Darmstadt, Darmstadt, Germany
A TetR-binding aptamer as versatile regulatory element
1030: Professor Dr Günter Mayer (V)
Professor, University of Bonn, Life & Medical Sciences Institute (LIMES), Chemical Biology, Bonn, Germany
The PAL:aptamer system: Optoribogenetic control of gene expression in mammalian cells
1050: Professor Marit Nilsen-Hamilton
Professor, Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University and Faculty Scientist, Ames Laboratory, US Department of Energy, Ames, IA USA
DNA aptamers to Ebola virus; Selection, analysis, and application
1110: Dr Anna Miodek
Aptamer Scientist, Ixaka, Villejuif Bio Park, 1 Mail du Professeur Georges Mathé, VILLEJUIF, France
Towards preclinical development of CD3-specific DNA aptamers
1130: Dr Marcus Menger
Group Leader, Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses (IZI-BB), Am Mühlenberg, Potsdam, Germany
Aptamers as specific recognition elements in medical diagnostics
1150: Miss Perrine Lasserre
Graduate Research Student, Dept of Biomedical Engineering, University of Strathclyde, Glasgow, UK
Aptasensor development and optimisation for rapid, low-cost environmental monitoring of antibiotics
1210: Miss Blandine Billet
Graduate Research Student, University Grenoble Alpes, CEA, Grenoble, France
Aptamer Switches Regulated by Post-Transition/Transition Metal Ions
1230: Lunch and networking at St Hilda’s College
Session 5 (virtual/in-person): Chair TBA
1310: Mr Thomas Binet
Graduate Research Student, Université de technologie de Compiègne, UPJV, CNRS, Enzyme and Cell Engineering, Centre de recherche Royallieu – Compiègne Cedex, France
In silico 3D structure prediction of aptamers
1330: Mr Jordan Cossu
Graduate Research Student, University Grenoble Alpes, CEA, Grenoble, France
Selection and characterization of single-stranded DNA aptamers against the CD-20 antigen
1350: Miss Meihua Gong
Graduate Research Student, Université de technologie de Compiègne, UPJV, CNRS, Enzyme and Cell Engineering, Centre de recherche Royallieu – Compiègne Cedex, France
A new tool to purify methylated peptide from bacteria in order to study bacterial mechanosensing
1410: Miss Auriane Guitton-Auberty
Graduate Research Student, University Grenoble Alpes, CEA, Grenoble, France
Aptamer-Target Crosslinks Formation
1430: Miss Vipasha Sharma (V)
Graduate Research Student, Biomolecular Electronics and Nanotechnology Group, CSIR- Central Scientific Instruments Organisation, Chandigarh, India
Rationally Truncated high affinity Aptamer based Electrochemical Detection of Stress Hormone on Graphene Quantum Dots Modified Screen Printed Electrodes
1450: Closing remarks by Dr Janjic and close