(Subject to change)
All talks will be held in the The Edward Boyle auditorium, The Jacqueline du Pré Music Building, St Hilda’s College (Oxford).
08.30-09.20: Registration, welcome coffee and networking
09.20: Housekeeping announcements
09.25: Welcome by the symposium chair
09.30: Dr David Bunka
Co-director and CTO of Aptamer Solutions and Aptamer Diagnostics Ltd, UK
Title: Aptamers: Where’ve we been, where are we now and where are we going
10.00: Professor Said Ismail
Head, Molecular Biology Research Laboratory, Medical School, University of Jordan, and, Head, Molecular Diagnostics Lab, Jordan University Hospital, Amman, Jordan
Title: Aptamers as Potential Tyrosine Kinase Inhibitors
10.30: Professor Dr Ulrich Hahn
University of Hamburg, Department Chemistry, Institute for Biochemistry and Molecular Biology, Martin-Luther-King-Platz 6, Hamburg, Germany
Title: Cell surface protein specific aptamers for diagnosis, therapy and cargo delivery into target cells
11.00: Refreshment break, posters, exhibition, networking
11.30: Dr Sarah Shigdar
Lecturer in Medical Sciences, Deakin University, VIC, Australia
Title: Getting the brain to take its medicine
11.50: Professor Yoshikazu Nakamura
President and CEO, Ribomic Inc, Tokyo, Japan
Title: Aptamer therapeutics targeting pain and lung fibrosis
12.10: Dr Georg Mahlknecht
Immunology Department, Weizmann Institute of Science, Israel
Title: Aptamers targeting growth factor receptors
12.30: Dr Paloma H Giangrande
Associate Professor, Department of Internal Medicine, University of Iowa, USA
Title: RNA aptamer smart drug for the treatment of vascular injury
13.00: Lunch and networking
14.00: Professor Nagy Habib
Professor of Hepatobiliary Surgery, Faculty of Medicine, Department of Surgery & Cancer, Imperial College London, UK
Title: Targeted RNA activation
14.30: Dr Vittorio de Franciscis
Research Director, CNR Institute of Experimental Endocrinology and Oncology, Naples, Italy
Title: Combined selective targeting of cancer stem cells by aptamer-miRNA/antimiR conjugates
15.00: Professor Dr Beatrix Suess
Synthetic Genetic Circuits, Technical University of Darmstadt, 03 064 Schnittspahnstraße 1064287, Darmstadt, Germany
Title: Control of alternative splicing by engineered riboswitches
15.30: Refreshment break, posters, exhibition, networking
16.00: Dr Thomas Schubert
2bind GmbH, Regensburg, Bavaria, Germany
Title: Characterisation of aptamer-target interactions using MicroScale Thermophoresis
16.30: Professor Dr Günter Mayer
Life and Medical Sciences (LIMES)- Institute, University of Bonn, Gerhard-Domagk-Str. 1, Bonn, Germany
Title: A modular approach to nucleobase-modified aptames
17.00: Professor Karolien De Wael
AXES Research Group, Department of Chemistry, Antwerp University, Belgium
Title: Electrochemical aptasensing devices
17.20: Dr Arnaud Buhot
University of Grenoble/CNRS/CAE, France
Title: Gold nanoparticles SPRi enhanced signal for small molecules detection with split aptamer
17.40: Dr Julian Tanner
Associate Professor, Department of Biochemistry, University of Hong Kong, China
Title: DNA aptamers for point-of-care malaria diagnosis – from crystal structure to clinical application using Aptamer Tethered Enzyme Capture (APTEC)
18.00: Dr Graeme Doran
Director of Genomic Assays, FireFly BioWorks, Cambridge, MA, USA
Title: Direct quantification of small nucleic acid delivery to tissues
18.30: Close
19.00: NETWORKING DINNER (By invitation or prior booking only)
9.20: Dr Jean-Jacques Toulmé
Director, Institut Européen de Chimie et Biologie, Pessac, France
Title: Aptamer driven supra-molecular assembly
09.50 Dr David Porciani
NEST – Scuola Normale Superiore, Piazza San Silvestro 12 Pisa, Italy
Title: Aptamer-mediated co-delivery of doxorubicin and NF-kB decoy enhances chemosensitivity of pancreatic tumor cells
10.20: Dr Nebojsa Janjic
SomaLogic, Inc, 2945 Wilderness Place, Boulder, CO, USA
Title: Modified aptamers with enhanced chemical diversity as essential tools for biomedical research
10.40: Refreshment break, posters, exhibition, networking
11.10: Professor Weian Zhao
Assistant Professor, Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, CA, USA
Title: Microencapsulated aptamer sensors for digital quantification of blood biomarkers
11.30: Dr Maureen McKeague
Bioengineering Department, Stanford University, USA
Title: Advancing a development pipeline for RNA switches through scalable measurement platform
11.50: Dr Yoann Roupioz
University of Grenoble/CNRS/CAE, France
Title: On the use of aptamer microarrays as a platform for the exploration of human prothombin/thrombin conversion
12.10: Mr Nam Nguyen Quang
CEA, Molecular Imaging Research Center, France
Title: Improvement of aptamers combining doped-SELEX and next-generation sequencing
12.30: Lunch and close