Provisional Agenda

(Subject to change: The conference may finish slightly earlier or later than the advertised time)

Presentation language: English

Venue: The Jarvis Doctorow Hall, St Edmund Hall, Queen’s Lane, Oxford, UK

Time Zone: All times mentioned refer to Greenwich Mean Time (GMT/London).

Password and links: Registered conference delegates will be sent joining information and conference access links a few days before the conference.

World Time Converters: https://greenwichmeantime.com and https://www.worldtimebuddy.com

NB: Due to the hybrid nature of the agenda and the wide geographical locations of our speakers, it may not have always been possible to group together related presentations.


Day 1: Monday 18th March 2024

0900: Registration and welcome coffee

0955: Housekeeping


Sensors/biosensors and probes-I

1000: Dr Katsunori Horii (V)
Executive Professional & Advanced Technologist, Digital Healthcare Business Development Office, NEC Solution Innovators, Ltd, Tokyo, Japan
Aptamar sensor for visualizing immune barrier

1020: Professor Dr Günter Mayer
Professor, University of Bonn, Life & Medical Sciences Institute (LIMES), Chemical Biology, Bonn, Germany
Modular approach for rapid identification of RNA-based sensors

1040: Dr Nabojsa Janjic & Dr Xiaotang Lu (Harvard University)
Chief Science Officer, SomaLogic Inc, Boulder, CO, USA
Aptamers as Histochemical Probes

1100: Professor Maureen McKeague
Assistant Professor of Chemistry, Department of Chemistry & Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada
Fluorescent aptamer biosensors


1120: Refreshment break, networking and posters


1200: Professor Philip Johnson
Professor of Chemistry, Department of Chemistry, York University, Toronto, Ontario, Canada
From SELEX to Sensor


Sensors/biosensors and probes-II

1220: Dr Miguel António Dias Neves
Assistant Investigator (Professor), Institute for Research and Innovation in Health (i3S), University of Porto, Porto, Portugal
AptaBody: a universal aptamer-based signal transduction system for high-throughput biosensing

1240: Mr Ho Ping Siu
Doctoral Research Student, School of Biomedical science, University of Hong Kong Hong Kong SAR, China
Segregative liquid-liquid phase separation for biomarker concentration and electrochemical aptamer biosensor application

1300: Professor Julian Tanner
Professor, School of Biomedical Sciences, University of Hong Kong, Hong Kong SAR, China
Symmetry, structure and function of aptamer-functionalised nucleic acid nanostructures


1320: Lunch, networking and posters


Structure, modification and selection

1420: Professor Bruce Sullenger
Joseph and Dorothy Beard Professor, Department of Surgery, Cardiovascular Biology Laboratory, Duke University School of Medicine, Durham, North Carolina, USA
Hirudin inspired aptamer-small molecule conjugates: engineering potent, selective, and reversible EXosite-ACTive site (EXACT) inhibitors

1440: Professor Dr Beatrix Suess
Professor, Synthetic Genetic Circuits, Technical University of Darmstadt, Darmstadt, Germany
Capture versus Conventional SELEX – a comparison

1500: Dr Nick Turner
EPSRC Established Career Fellow and Professor of Bioanalytical Chemistry, Department of Chemistry, University of Sheffield, Sheffield, UK
aptaMIPs: Applying the Principle of Molecular Imprinting to Stabilise Aptamer Sequences

1520: Professor Noemí de los Santos Álvarez
Professor of Analytical Chemistry, Departament of Physical and Analytical Chemistry, University of  Oviedo, Oviedo, Spain
3D aptamer structure matters: computational-assisted aptamer optimization for electrochemical sensing


1540: Refreshment break, networking and posters


1620: Professor Sergey N Krylov
Distinguished Research Professor and Director, Centre for Research on Biomolecular Interactions, Department of Chemistry, York University, Toronto, Ontario, Canada
Quantitative Characterization of Stringency in SELEX

1640: Professor Marit Nilsen-Hamilton
Professor, Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA
Structural flexibility and population ensembles; Setting criteria for aptamers

1700: Dr Cameron Mackereth
Senior Scientist, University of Bordeaux, ARNA Laboratory, CNRS UMR, Bordeaux, France
NMR spectroscopy and mass spectrometry studies of the ochratoxin A and dopamine aptamer complexes

1720: Miss Sofie Schellinck
Doctoral Research Student, Department of Organic and Macromolecular Chemistry, Ghent University, Ghent, Belgium
Uncovering the Molecular Life of the Testosterone Binding Aptamer TESS.1 with NMR: Complex Formation and Structure Switching Mechanism


Therapeutics

1740: Mr Brian J Thomas (V)
Doctoral Research Student, Dept Molecular Microbiology & Immunology, Bond Life Sciences Center, University of Missouri School of Medicine, Columbia, MO, USA
Biodistribution of anti-EGFR and anti-cMET aptamer nanostructures targeting lung adenocarcinoma

1800: Close of day 1

1900: Networking dinner (on a ‘pay-as-you-eat’ basis – arrangements and venue to be confirmed)


Day 2: Tuesday 19th March 2024

0955: Housekeeping


Therapeutics

1000: Dr Yasmin Liu (V)
Senior Scientist, Forensic Research & Development, Institute of Environmental Science and Research, 5022 Porirua, New Zealand
Disposable Electrochemical Aptamer-based Biosensor for Cocaine Detection with Enhanced Response in Oral Fluid

1020: Dr Chizuko Koseki
President & CEO, TAGCyx Biotechnologies, Inc, Meguro, Tokyo, Japan
Application of Xenoligo® technology platform generating DNA aptamers

1040: Dr Jaqueline Lourdes Rios
Assistant Professor, Regenerative Medicine Utrecht, Department of Orthopaedics, University Medical Center Utrecht, Utrecht, The Netherlands
APTAMER-OA: Aptamer-based therapeutics for osteoarthritis


1100: Refreshment break, networking and posters


1140: Dr Yuanyuan Yu
Assistant Professor, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China
Therapeutic Aptamer Targeting Sclerostin Loop3 for Promoting Bone Formation without Increasing Cardiovascular Risk

1200: Miss Claire Husser
Doctoral Research Student, Université de Strasbourg, Architecture et Réactivité de l’ARN, Team “Digital Biology of RNA”, Institut de Biologie Moléculaire et Cellulaire du CNRS, France
Selection of β-lactamase inhibiting aptamers by ultrahigh-throughput microfluidic screening

1220: Mr Mickaël Guerin
Doctoral Research Student, Génie Enzymatique et Cellulaire (GEC), UMR 7025 CNRS, Université de Technologie de Compiègne, Compiègne, France
Combining FluMag and cell SELEX to select a probe which detect Borrelia burgdorferi, the etiological agent of Lyme borreliosis


1240: Lunch break, networking and posters


1300: Dr Benjamin D Almquist
Associate Professor & Director, Biomedical Technology Ventures Programme, Department of Bioengineering, Imperial College London, London, UK
Pilfering Patient Pharmacies – Using Bioinspired Aptamers to Drive Tissue Repair

1320: Miss Mareike De Pascali
Doctoral Research Student, Technical University of Munich, TUM School of Natural Sciences, Department of Bioscience, Garching, Germany
From screening of sequence mutations to the optimized kinetic parameters of aptamers

1340: Mr Zhuqian Wang
Doctoral Research Student, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China
Targeting S100A9 to reverse failure of anti-TNF therapy in rheumatoid arthritis

1400: Miss Duoli Xie
Doctoral Research Student, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China
Generation of cytotoxic aptamers specifically targeting fibroblast-like synoviocytes by CSCT-SELEX for treatment of rheumatoid arthritis

1420: Miss Jie Huang
Doctoral Research Student, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China
Aptamers as a Promising Therapeutic Approach for Rheumatoid Arthritis: Targeting the ESM1 Protein

1440: Close


 

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