Dr Mark Lindsay, UK
Role of microRNAs in the innate immune response
Dr Marcus Peter, USA
The role of microRNAs in tumour progression
Dr Alberto Gulino, Italy
MicroRNA control of cerebellar neural progenitors and medulloblastoma cells
Professor Cy Stein, USA – *Keynote Speaker*
Efficient Gene Silencing by the Gymnotic Delivery of Oligonucleotides
Dr Jörg Vollmer, Pfizer-Coley, Germany
Delivery systems and their use for single- and double-stranded RNA therapeutics
Professor Achim Aigner, Germany
Anti-tumor effects of polyethylenimine ( PEI)-complexed siRNAs or shRNAs targeting tumor-relevant genes
Dr Dmitry Samarsky, RXi Pharma, USA
The Role of RNAi Compound Potency and Delivery in In Vivo Efficacy
Dr Lars Dölken, Germany
Identification and characterisation of MCMV encoded miRNAs in vitro and in vivo
Dr Nikolas Machuy, Germany
Global identification and therapeutic knock down of host cell factors essential for influenza replication
Dr Venugopal Nair, UK
Role of avian herpesvirus-encoded microRNAs in pathogenesis
Dr Martin Kreutz, Qiagen, Germany
Title: Quantification and functional analysis of miRNA in mammalian cells
Dr Stephanie Urschel, Thermo Scientific, Germany
Micro-RNA (miRNA) Mediated Gene Regulation: Analyzing miRNAs involved in biological processes
Dr Natal’ya Kruglova, Russia
Structurally modified anti-MDR1 siRNAs with selective 2’-O-methyl modifications: Biological activity and nuclease resistance
Dr Zubair Ahmed, UK
Protection of Retinal Ganglion Cells from Apoptosis Induced by Optic Nerve Crush by Intra-vitreal Injection of siRNA
Dr Olaf Heidenreich, UK
Fusion Genes: Lime Leafs in the Leukaemic Armour?
Professor Nick Proudfoot, UK
Autoregulation of convergent RNAi genes by transient heterochromatin formation inS. pombe
Professor Rene Bernards, The Netherlands – *Keynote Speaker*
Functional genetics approaches to identify drug response biomarkers
Dr Mark Behlke, IDTDNA, USA
U1 Adaptors: A novel gene silencing technology
Professor Ben Berkhout, The Netherlands
RNAi gene therapy for HIV-AIDS
Professor Georg Sczakiel, Germany
Title: Cellular uptake of naked functional oligonucleotides: the phosphorothioate-stimulated delivery of siRNA indicates new routes for cellular and intracellular transport
Dr Gilles Divita, France
Peptide-based nano-particle for in vivo delivery of siRNAs
Dr Raymond Schiffelers, The Netherlands
PCI facilitates endosomal escape and improves silencing efficiency, in vitro and in vivo
Dr Tatiana Kabilova, Russia
Title: Antiproliferative action of immunomodulating siRNAs: Dependence on their sequences