Speakers & Agenda

Speakers and Agenda

(Subject to change)

All talks will be held in the The Edward Boyle auditorium, The Jacqueline du Pré Music Building, St Hilda’s College (Oxford).


08.00-08.50: Registration, Networking, Exhibition and welcome coffee

08.50: Welcome and housekeeping

08.55: Opening by Professor Dr Beatrix Suess

09.00: INSOAP updates by Dr Sarah Shigdar

Session 1: SELEX – New technological developments
Chair Dr David Bunka

09.10: Professor Thomas Brown, University of Oxford, United Kingdom
Synthesis of chemically modified oligonucleotides for the production of high-affinity aptamers

09.40: Dr Gregory Penner, President & CEO, NeoVentures Biotechnology Inc, Canada
FRELEX. free-free selection of aptamers

10.10: Dr Nathalie Vollmer, Horiba Scientific, France
Multiplex quantification of small molecule targets with SPRi analysis

10.30: Refreshment break, exhibition, posters and networking

11.10: Professor Chin-Yih Hong, Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taiwan
Multiplex Immunoassays Using ssDNA Aptamers Generated by Magnetic-Assisted Rapid Aptamer Selection (MARAS)

11.30: Dr Bill Jackson, Base Pair Biotechnologies, USA
Applications of newly discovered aptamers in a variety of biosensors and assay formats

11.50: Professor Darryl J Bornhop, Professor of Chemistry, Vanderbilt University, TN, USA
Backscattering interferometry marries aptamer-based assays to enable quantitation of nerve agent metabolites and human cytomegalovirus in urine at clinical relevant levels

12.10: Dr Michael Blank, AptaIT GmbH, Germany
Improved Aptamer Identification and Optimization by Usage of Next Generation Sequencing

12.30: Lunch, exhibition, posters and networking

Session 2: Small molecule binding aptamer–Characterization and their application for gene control
Chair Professor Darryl Bornhop

13.40: Dr Philip Johnson, York University, Canada
Understanding Ligand Binding by the Cocaine-Binding Aptamer

14.00: Professor Dr Jörg S Hartig, Department of Chemistry, University of Konstanz, Germany
Engineering of synthetic riboswitches based on ribozyme expression platforms

14.30: Professor Dr Beatrix Suess, Technische Universität Darmstadt, Germany
Application of aptamers in the control of alternative splicing by engineered riboswitches

15.00: Professor Dr Uli Hahn, Hamburg University, Germany
Aptamers to inhibit cancer cell adhesion

15.30: Refreshment break, exhibition, posters and networking

Session 3: Aptamers as diagnostic tools
Chair Professor Said Ismail

16.00: Dr David Bunka, The Aptamer Group, United Kingdom
Novel Based Aptamer Biomarker Discovery

16.30: Processor Tony Cass, Imperial College London, United Kingdom
Engineering Aptamers for Use in Biosensors and Point of Decision Testing

17.00: Dr Julian Tanner, University of Hong Kong, China
Progress in aptamer-mediated malaria diagnosis

17.20: Dr Ana María de Lucas Cerrillo, Centro de Astrobiología (INTA/CSIC), Spain
RNA and DNA aptamers targeting HCV CORE protein and its applicability to HCV diagnosis

17.40: Dr Marimuthu Citartan, Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, Malaysia
REPORA-6 RNA aptamer, an agent in the aptamer-based capture assay (AptaCapture) of Erythropoietin (EPO) in doping detection


19.15 Dinner (entry by ticket only)


08.50: Welcome and housekeeping

Session 4: Therapeutic aptamers
Chair Professor Beatrix Suess

9.00: Professor Yoshikazu Nakamura, RIBOMIC Inc, Japan
Dual therapeutic action of a neutralizing anti-FGF2 aptamer in bone diseases and bone cancer pain

09.30: Professor Nicola Stonehouse, University of Leeds, United Kingdom
Manipulating viral protein-protein interactions with RNA aptamers

10.00: Professor Said Ismail, University of Jordan, Jordan
Targeted gene silencing in cancer cells using Anti-CD44 aptamer-functionalized liposomes

10.30: Refreshment break, exhibition, posters and networking

11.00: Dr Sarah Shigdar, Deakin University, Australia
Aptamers as theranostic agents: the companion diagnostic test

11.30: Dr Sorah Yoon, Beckman Research Institute of City of Hope, USA
ApDCs (Aptamer Drug Conjugates) for targeted therapies in pancreatic cancer; from nucleic acid to chemotherapeutics

12.00: Mr Chao Liang, Hong Kong Baptist University, Hong Kong, China
Oligopeptide aptamer-modified chalcone derivative specifically targets Smurf1 in osteoblasts and promotes bone formation

12.20: Lunch, exhibition, posters and networking

Session 5: Technologies
Chair Dr Sarah Shigdar

13.10: Miguel AD Neves, Department of Chemistry, York University, Toronto, ON, M3J 1P3, Canada
The Cocaine-Binding Aptamer: Structural and Thermodynamic Analysis of Two-Site Binding and Stem Length Variation

13.30: Rajesh Ahirwar, Academy of Scientific and Innovative Research, Delhi, India
Aptamer-mediated detection and targeting of estrogen receptor positive cells in human breast cancer

13.50: Dr Zhaofeng Luo, Core Facility Center for Life Sciences, University of Science and Technology of China (USTC), Hefei, PR China
Monitoring the aptamer selection progress by Q-PCR amplification curve

14.10: Closing remarks by the Symposium Chair and discussion

14.30: Close and departure