(Subject to change)
All talks will be held in the Edward Boyle Auditorium, JdP, St Hilda’s College.
0800: Registration
0830: Housekeeping
0840: Welcome by the Symposium Chair
0850: Welcome by the INSOAP President
Chair: Professor Philip Johnson, York University, Canada
0900:
Professor Jesper Wengel
Professor and Center Director, BioNEC – A VKR Center of Excellence, FKF – University of Southern Denmark, Odense, Denmark
Title: Novel aptamers based on LNA and UNA
0930:
Dr Xianbin Yang
Director of R&D, AM Biotechnologies, Houston, TX, USA
Title: X-Aptamers – Chemically modified aptamers that can be used for biomarker discovery
0950:
Dr Daniel Schneider
Senior Director, Technology Development, Boulder, CO, SomaLogic, USA
Title: Next Generation Aptamers: Enhancing Chemical Diversity with Multiple Pyrimidine Modifications
Chair: Professor Dr Beatrix Suess, Technical University of Darmstadt, Germany
1010:
Dr Gregory Penner
President & Founder, NeoNeuro SAS, 38 Rue de Berri, Paris, France
Title: Development of aptamers for the treatment and diagnosis of Alzheimer’s disease
1030: Refreshments, exhibition, posters
1110:
Professor Dr Ulrich Hahn (Symposium Chair)
University of Hamburg, Department Chemistry, Institute for Biochemistry and Molecular Biology, Hamburg, Germany
Title: Selectin and Integrin Aptamers
1140:
Professor Yoshikazu Nakamura
CEO & President, Ribomic Inc, Japan
Title: Anti-FGF2 aptamer restores bone growth affected in Achondroplasia transgenic mice
1210:
Professor Fernando Pastor Rodriguez
Principal Investigator, Foundation for Applied Medical Research, Pamplona, Spain
Title: Targeting Co-Stimulation with Bi-Specific Aptamers to Melanoma Cancer Stem Cells
1230:
Dr Sarah Shigdar
Senior Lecturer in Medicine, Schoool of Medicine, Deakin University, Waurn Ponds, Australia
Title: Treating brain metastases with a bifunctional aptamer
1300: Group Photo, Lunch, exhibition, posters
Chair: Professor Yoshikazu Nakamura, Ribomic Inc, Japan
1400:
Professor Anthony Cass
Professor of Chemical Biology, Department of Chemistry, Institute of Biomedical Engineering, Imperial College London, UK
Title: Aptamers in Bioanalysis: from Lateral Flow to Nanopore Sensing
1430:
Dr Julian Tanner
Associate Professor & Coordinator of Education Division of Biochemistry, University of Hong Kong, PR China
Title: Aptamers for Malaria Diagnosis
1500:
Professor Victoria Calzada
Principal Investigator, Área de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la República, Montevideo-Uruguay
Title: Aptamers as molecular probes: multimodal imaging
1520: Refreshments, exhibition, posters
Chair: Professor Marit Nilsen-Hamilton, Iowa State University, USA
1600:
Dr David Bunka
Chief Technical Officer, Aptamer group, Bio Centre, Innovation Way, Heslington, York, UK
Title: Aptabind; Enabling Protein Purification
1630:
Dr Duncan Borthwick
Staff Scientist, Dynamic Biosensors GmbH, Lochhamer Str 15, Planegg, Germany
Title: A Regenerating Biochip, Modelling the Kinetics of Aptamer Interactions using switchSENSE® Technology
1650:
Dr Sean Dembowski
Department of Chemistry, University of Minnesota–Twin Cities, 207 Pleasant St. SE, Minneapolis, MN, USA
Title: Isolating aptamers for membrane proteins using capillary electophoresis-SELEX
1710:
Mr John Goertz
Fischell Department of Bioengineering, University of Maryland, College Park, MD, USA
Title: A novel photocatalyzed colorimetric reaction for real-time biosensing with catalytic aptamers
1725: Close of Day 1
1730: INSOAP AGM (open to all attendees)
1800: Aptamers Board meeting (Aptamers editorial board members only)
1915: Networking dinner (by prior booking or invitation only)
Chair: Professor Fernando Pastor Rodriguez, Foundation for Applied Medical Research, Spain
0840:
Dr Terry Steele
Assistant Professor, School of Materials Science & Engineering, College of Engineering, Nanyang Technological University, Singapore
Title: Exploiting aptamer adaptive binding towards reversible aptasensors
0900:
Dr Meltem Avci-Adali
University Hospital Tuebingen, Dept of Thoracic and Cardiovascular Surgery, University Hospital Tübingen, Tübingen, Germany
Title: Biofunctionalization of hydrogels with aptamers for tissue engineering applications
0920:
Professor Philip Johnson
Associate Professor, Department of Chemistry, York University, Toronto, ON, M3J 1P3, Canada
Title: Two-Site Binding by the Cocaine-Binding Aptamer
Chair: Professor Dr Ulrich Hahn, University of Hamburg, Germany
1000:
Professor Dr Beatrix Suess (Aptamers 2016 Chair)
Professor of Synthetic Biology, Technical University of Darmstadt, Germany
Title: Development of novel engineered riboswitches
1030: Refreshments, exhibition, posters
1100:
Dr Florian Groher
Department of Biology, Technical University Darmstadt, Schnittspahnstr 10, Darmstadt, Germany
Title: In Vivo Screening For New Synthetic Riboswitches
1120:
Dr Carlos Penedo
Principal Investigator, Laboratory for Biophysics and Biomolecular Dynamics, SUPA School of Physics and Astronomy, University of St. Andrews, St Andrews, United Kingdom
Title: Single-molecule FRET structural analysis of nascent aptamer-expression platform riboswitch sequences along their transcriptional pathway
1150:
Professor Dr Mario Mörl
Biochemistry and Molecular Biology, Institute for Biochemistry, Leipzig University, Brüderstr 34, Leipzig, Germany
Title: From Plug & Pray to Plug & Play – Aptamer-based transcriptional Riboswitches
1220: Lunch, exhibition, posters
Chair: Dr David Bunka, Aptamer Group, UK
1310:
Dr Muslum Ilgu
Aptalogic Inc, Molecular Biology Building, Ames, Iowa, USA
Title: Evaluation of MC-SYM structural predictions for an RNA aptamer with additional base stacking calculations and fluorescence of 2AP-substituted aptamers
1330:
Dr Gregory Penner
President & CEO, NeoVentures Biotechnology Inc, 5 York St, London, Ontario, N6A 1A1, Canada
Title: Using next generation sequence analysis to understand aptamer selection and application
1350:
Dr Maureen McKeague
Department of Health Sciences and Technology, ETH Zürich, Schmelzbergstrasse 9, Zürich, Switzerland
Title: Computational approaches for improving aptamers and their application to metabolic engineering
1410: Discussion Closing remarks by Professor Dr Ulrich Hahn
1430: Close and departure