Provisional Agenda

(Subject to change: The conference may finish slightly earlier or later than the advertised time)

All times mentioned refer to British Standard/Summer Time (BST) – London/GMT+01:00. Registered delegates will be sent joining information a few days before the conference.

World Time Converter:

Presentation language: English

Venue: Edward Boyle Auditorium, The Jacqueline du Pré Music Building (JdP), St Hilda’s College, Oxford

Day 1: Monday, 4th April

0900: Registration and refreshments

0940: Housekeeping

0945: Welcome by Dr Nebojsa Janjic

0950: INSOAP/Aptamers updates by Professor Sarah Shigdar

Session 1 (Virtual): Chair Professor Sarah Shigdar

1000: Dr Katelyn Richards
Research Scientist, WearOptimo, Woolloongabba, Queensland, Australia
Rational maturation and library design for the development of Troponin-binding aptamers for in vivo biosensing applications

1020: Dr Hiroko Miki
Research Scientist, Corporate Research & Development Center, Toshiba Corporation, Kanagawa, Japan
Maximizing the Immobilized Amount of DNA Aptamer Probes on Graphene Odor Sensors

1040: Mr Lin Wang
Graduate Research Student, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Self-Assembly of DNA Tiles with G-quadruplex DNAzyme Catalytic Activity for Sensing Applications

1100: Dr Marimuthu Citartan
Senior Lecturer, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas, Penang, 13200 Malaysia
Secura-3 RNA aptamer as a promising molecular recognition element against the global transcription factor Human Pituitary Tumour Transforming Gene 1 (PTTG1)

1120: Miss Safiye Jafari
Graduate Research Student, Department of Health Sciences and Technology, ETH Zürich, Schmelzbergstrasse 9, 8092 Zürich, Switzerland
Development of electrochemical aptasensor for detection of aflatoxin B1 in cereals

1140: Miss Mengping Liu
Graduate Research Student, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Evolution of BMP-2-specific DNA aptamers for promoting BMP-2-induced osteogenesis in ECM mimetic scaffolds

1200: Professor Ajda Çoker-Gürkan
Professor, Department of Molecular Biology and Genetics, Biruni University, Topkapı, Istanbul, Turkey
X-aptamers against Growth Hormone Releasing Hormone (1-29) induces apoptosis via autophagy and endoplasmic reticulum stress in MiaPaca-2 and HT-29 cancer cells

1220: Miss Krisztina Percze
Graduate Research Student, Department of Molecular Biology, Semmelweis University, Budapest, Hungary
Tryptophan-like side chain holding aptamers inhibit RSV infection

1240-1310: Flash-talks-I

Presenters: Cao, Coombes, Guzdek, Kerler, Legen, Nakhjavani, Puchala, Samokhvalov, Singh, Sramkova, Svehlova, Tungsirisurp, Volek

 1310: Lunch and networking at St Hilda’s College

Session 2 (virtual/in-person): Chair Dr Nebojsa Janjic

1400: Dr Robert Batchelor
Head of Biosensors Group, Nutromics Pty Ltd, Brunswick, Victoria, Australia
Electrochemical aptamer-based sensors: a platform technology supporting seconds-resolved, real-time molecular monitoring in the living body

1420: Dr Nebojsa Janjic
Chief Science Officer, SomaLogic Inc, Boulder, CO, USA
Aptamer-based analysis of plasma proteome of growing tumors

1440: Professor Philip Johnson
Professor of Chemistry, Department of Chemistry, York University, Toronto, Ontario, Canada
Structure-Function Studies of Aptamer-Small Molecule Complexes

1500: Professor Larry Gold (Keynote Speaker) (V)
Professor of Molecular Cellular & Developmental Biology, SomaLogic Inc, and College of Arts and Sciences, University of Colorado Boulder, Boulder, CO, USA
Broad Proteomics and Target Identification for Pain Therapeutics: Making the Leap from Correlation to Causality

1530: Coffee and networking at St Hilda’s College

Session 3: (Virtual): Chair Professor McKeague

1600: Professor Anna Marie Pyle
Sterling Professor of Molecular, Cellular and Developmental Biology and Department of Chemistry; Investigator, Howard Hughes Medical Institute; Yale University, New Haven, CT, USA
A Modified DNA Aptamer Mimics Viral RNA Utilizing a Unique Molecular Recognition Strategy with a Highly Unusual Structure

1620: Professor Bruce Sullenger
Dorothy W Beard Distinguished Professor of Experimental Surgery, Duke University, Durham, North Carolina, USA
Recanalization of Canine Large Vessel Occlusion 6 Hours Post Stroke by and IND Enabling Studies for VWF Aptamer DTRI-031

1640: Dr Gregory Penner
President & CEO, NeoVentures Biotechnology Inc, London, Canada & President & Founder, NeoNeuro SAS, Paris, France
Neomers, a novel approach to aptamer selection

1700: Ms Micaela Belleperche
Graduate Research Student, Department of Chemistry, McGill University
Montreal, Quebec, Canada
Fluorescent detection of 8-Oxoguanine using a structure-switching aptamer

1720-1750: Flash-talks-II

Presenters: Berman/Hertz, Chao, Choukeife, Churcher, Esmaeili, Kaiyum, LeDortz, Lewis, Martinez-Liu, Osborne, Mitchell, Schellinck, Shoara, Torres-Vazquez, Toscano

1900: Networking dinner

Day 2: Tuesday, 5th April

1000: Welcome

Session 4 (virtual/in-person): Chair TBA

1010: Professor Dr Beatrix Suess (V)
Professor, Synthetic Genetic Circuits, Technical University of Darmstadt, Darmstadt, Germany
A TetR-binding aptamer as versatile regulatory element

1030: Professor Dr Günter Mayer (V)
Professor, University of Bonn, Life & Medical Sciences Institute (LIMES), Chemical Biology, Bonn, Germany
The PAL:aptamer system: Optoribogenetic control of gene expression in mammalian cells

1050: Professor Marit Nilsen-Hamilton
Professor, Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University and Faculty Scientist, Ames Laboratory, US Department of Energy, Ames, IA USA
DNA aptamers to Ebola virus; Selection, analysis, and application

1110: Dr Anna Miodek
Aptamer Scientist, Ixaka, Villejuif Bio Park, 1 Mail du Professeur Georges Mathé, VILLEJUIF, France
Towards preclinical development of CD3-specific DNA aptamers

1130: Dr Marcus Menger
Group Leader, Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses (IZI-BB), Am Mühlenberg, Potsdam, Germany
Aptamers as specific recognition elements in medical diagnostics

1150: Miss Perrine Lasserre
Graduate Research Student, Dept of Biomedical Engineering, University of Strathclyde, Glasgow, UK
Aptasensor development and optimisation for rapid, low-cost environmental monitoring of antibiotics

1210: Miss Blandine Billet
Graduate Research Student, University Grenoble Alpes, CEA, Grenoble, France
Aptamer Switches Regulated by Post-Transition/Transition Metal Ions

1230: Lunch and networking at St Hilda’s College

Session 5 (virtual/in-person): Chair TBA

1310: Mr Thomas Binet
Graduate Research Student, Université de technologie de Compiègne, UPJV, CNRS, Enzyme and Cell Engineering, Centre de recherche Royallieu – Compiègne Cedex, France
In silico 3D structure prediction of aptamers

1330: Mr Jordan Cossu
Graduate Research Student, University Grenoble Alpes, CEA, Grenoble, France
Selection and characterization of single-stranded DNA aptamers against the CD-20 antigen

1350: Miss Meihua Gong
Graduate Research Student, Université de technologie de Compiègne, UPJV, CNRS, Enzyme and Cell Engineering, Centre de recherche Royallieu – Compiègne Cedex, France
A new tool to purify methylated peptide from bacteria in order to study bacterial mechanosensing

1410: Miss Auriane Guitton-Auberty
Graduate Research Student, University Grenoble Alpes, CEA, Grenoble, France
Aptamer-Target Crosslinks Formation

1430: Miss Vipasha Sharma (V)
Graduate Research Student, Biomolecular Electronics and Nanotechnology Group, CSIR- Central Scientific Instruments Organisation, Chandigarh, India
Rationally Truncated high affinity Aptamer based Electrochemical Detection of Stress Hormone on Graphene Quantum Dots Modified Screen Printed Electrodes

1450: Closing remarks by Dr Janjic and close


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