• RNAi 2015: Short & Long Non-coding RNAs
    10th International Conference & Exhibition
    24-26 March 2015
    St Hilda's College, Oxford, UK

    Co-hosted Symposium, CRISPR 2015 OXFORD, 23 March 2014, Oxford, UK
  • RNAi 2015: Short & Long Non-coding RNAs
    10th International Conference & Exhibition
    24-26 March 2015
    St Hilda's College, Oxford, UK

    Co-hosted Symposium, CRISPR 2015 OXFORD, 23 March 2014, Oxford, UK
  • RNAi 2015: Short & Long Non-coding RNAs
    10th International Conference & Exhibition
    24-26 March 2015
    St Hilda's College, Oxford, UK

    Co-hosted Symposium, CRISPR 2015 OXFORD, 23 March 2014, Oxford, UK
  • RNAi 2015: Short & Long Non-coding RNAs
    10th International Conference & Exhibition
    24-26 March 2015
    St Hilda's College, Oxford, UK

    Co-hosted Symposium, CRISPR 2015 OXFORD, 23 March 2014, Oxford, UK

Speakers & Agenda

Provisional Agenda
(Subject to change)

  • 14.00: Registration, welcome coffee, networking, exhibition

    Session 1: Chair Dr Mark Behlke

    Hannon

    15.00: Dr Greg Hannon - Keynote address
    Cold Spring Harbor Laboratory & the Cancer Research UK Cambridge Institute
    Title: Small RNAs and mammalian genomics

    15.50: Q&A with Dr Hannon

    16.00: Dr Anna Zampetaki
    Lecturer in Cardiovascular Biology, King’s College London, The James Black Centre, London, UK
    Title: Circulating microRNA networks as biomarkers in cardiovascular disease

    16.30: Refreshment break

    17.00: Dr Mark Perry
    Research Fellow on Airway Disease, National Heart & Lung Institute, Imperial College London, London, UK
    Title: MicroRNAs and lncRNAs in lung disease

    17.30: Professor Chris Murphy
    Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, NDORMS, University of Oxford, Oxford, UK
    Title: MicroRNAs in cartilage health and disease 

    18.00: Dr Dmitry Samarsky
    Executive Vice President, Technology & Business Development, RiboBio Co, China
    Title: RNAi therapeutics: from discovery to manufacturing

    18.30: Drinks reception (sponsored by RiboBio)

  • Session 2: Chair Dr David Carter

    09.00: Dr Sandor Batkai
    Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Hannover, Germany
    Title: Non-coding RNAs in cardiac disease

    09.30: Dr Mark Behlke
    Chief Scientific Officer, Integrated DNA Technologies, USA
    Title: Influence of Intracellular Localization on lncRNA Knockdown

    10.00: Dr Ryan Raver
    Sigma-Aldrich, USA
    Title: The Future of RNAi Screening: Complementary Technologies and Improvements

    10.30: Refreshment break, networking, posters, exhibition

    11.15: Professor Tudor A Fulga
    Associate Professor of Genome Biology, Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxord, UK
    Title: Deciphering miRNA-target regulation by site-specific genome engineering 

    11.45: Dr Annaleen Vermeulen
    Senior Scientist, GE Healthcare/Dharmacon, Lafayette, CO, USA
    Title: The Utility of CRISPR-Cas9 System Employing Synthetic RNAs to Validate Hits from an RNAi Functional Screen

    12.15: Professor Stephen Hart
    Experimental and Personalised Medicines, UCL Institute of Child Health, London, UK
    Title: Targeted nanocomplex formulations for siRNA therapy

    12.45: Lunch break, posters, exhibition

    Session 3: Chair Dr Dmitry Samarsky

    14.00: Dr Raymond Schiffelers
    Associate Professor, Clinical Chemistry and Haematology, Department of Pharmaceutical Sciences, UMCU,  UTRECHT, The Netherlands
    Title: In vivo delivery of therapeutic RNAs

    14.30: Dr Tobias Poehlmann
    Friedrich-Schiller-University of Jena, Spin-off project "Intelligent siRNA", Jena, Germany
    Title: Development of Tumor-toxic miRNA mimics 

    15.00: Professor Andrew Miller
    Founder and Chief Scientific Officer, GlobalAcorn Ltd (Advanced Therapeutics), UK, and Visiting Professor, King's College London, UK
    Title: Functional delivery of RNAi effectors; the universal challenge facing RNAi therapeutics

    15.30: Refreshment break, networking, posters, exhibition

    16.15: Dr Graeme Doran
    Director of Genomic Assays, Firefly BioWorks Inc, One Kendall Square, Cambridge, MA, USA
    Title: High throughput direct detection of miRNA from mammalian biofluids

    16.35: Professor Dr Georg Sczakiel
    Professor and Director, Institute of Molecular Medicine, University of Luebeck, Germany
    Title: Loading of human Argonaute-2 by siRNA involves target RNA

    17.05: Professor Ian Blagbrough
    Professor, Department of Pharmacy and Pharmacology, University of Bath, Bath, UK
    Title: TBA

    17.35: : Panel discussion: Current challenges and trends for RNAi/oligonucleotide therapeutics

    18.30: Close of Day 2

    19.00: Networking dinner (by invitation or prior booking only)

  • Day 3

    Session 4: Chair Professor Andrew Miller

    9.00: Professor Martin Bushell
    Deputy Director and MRC Senior Research Fellow, MRC Toxicology Unit, Leicester, UK
    Title: The complexity of small RNA-mediated gene silencing

    9.30: Dr Nicholas Dibb
    Reader, Faculty of Medicine, Department of Surgery and Cancer, Imperial College London, UK
    Title: The functional and evolutionary importance of isomiRs

    10.00: Refreshment break, networking, posters, exhibition

    10.30: Dr Iris Lavon
    Leslie and Michael Gaffin Center for Neuro-Oncology and Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Title: Circulating miR-10b and miR-21 reflect the antiangiogenic effect of bevacizumab treatment in patients with glioblastoma (GBM)

    11.00: Professor Gerry Melino
    Head of 'Apoptosis & Cancer' Section, MRC Toxicology Unit, Leicester, UK
    Title: The role of microRNAs in epithelial stemness

    11.30: Dr Mark S Wilson
    Group Leader, Division of Molecular Immunology, National Institutes for Medical Research. MRC, London, UK
    Title: MicroRNAs in immune cells

    12.00: Dr Dave Carter
    Senior Lecturer, Oxford Brookes University, Oxford, UK
    Title: Exosomes and miRNAs; potential star players in the response to cancer therapy

    12.30: Dr M Zeeshan Danish
    Division of Drug Delivery and Tissue Engineering, School of Pharmacy, University of Nottingham, Nottingham, UK
    Title: Formulation Optimization and Characterization of Novel Bio-reducible Cross-linked siRNA Polyplexes for Gene silencing

    12.45: Lunch and close of conference