Thank you for considering to present your work as a poster at RNAi 2016.
Please prepare your poster in A1 portrait format (59cm wide x 84cm long). Please do not laminate your poster. Posters larger than A1 will only be displayed subject to the availability of space. Further information about poster sizes can be found on the following link:
Posters will be displayed for the full duration of the conference. Please shadow your posters during break times to answer any questions.
Please ensure you have appropriate permissions for the publication of your abstract from the original copyright holders. Should you wish your abstract not to be published, please notify us in writing at the time of abstract submission.
Invitation to submit full manuscript: RNAi 2016 presenters are invited to submit full manuscript to the Journal of RNAi and Gene Silencing. The deadline for sending full manuscripts is 30 March 2016. The conference will cover the basic open-access publication charges of accepted manuscripts.
(Presenters in Bold)
If your abstract has been accepted for presentation but it does not appear in the list below, please let us know as soon as possible by email on RNAiOxford@gmail.com.
High-throughput, Purification-free, Multiplexed Profiling of Circulating miRNA for Discovery, Validation, and Diagnostics
Juan Hidalgo de Quintana, M. Tackett, G. Doran, C. Rafferty, A. Windemuth, J. Tytell, D. Pregibon
Abcam plc, 330 Cambridge Science Park, Cambridge, CB4 0FL, UK
Abstract: We have developed the Multiplexed Circulating microRNA assay that allows the detection of up to 68 microRNA targets per sample. The assay combines particlebased multiplexing, using patented Firefly hydrogel particles, with single step RT-PCR signal. Thus, the Circulating microRNA assay leverages PCR sensitivity while eliminating the need for separate reverse transcription reactions and mitigating amplification biases introduced by target-specific qPCR. Furthermore, the ability to multiplex targets in each well…
Regulation of small non-coding RNAs expression in response to heat shock in Drosophila melanogaster
Sergei Yu. Funikov 1, Sergei S. Ryazansky 2, Alexander A. Kanapin 3, Elena S. Zelentsova 1, David G. Garbuz 1, Mikhail B. Evgen’ev 1, Olga G. Zatsepina 1
1 Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russian Federation
2 Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russian Federation
3 University of Oxford, Oxford, UK
Abstract: Any biological system strives to maintain a dynamic balance through coordinated biochemical reactions. However, even short-term environmental change, such as temperature elevation (heat shock, HS) forces the body to adapt by adjusting the basic program of gene expression. One of the mechanisms by which it is possible to achieve rapid impact on cellular metabolism is the regulation of the microRNA expression and function. Furthermore, stress may serve as an inductor of genomic instability, and, hence, lead to…