See you at:

Aptamers2014 (24-25 March 2014, Oxford, UK)

RNAi2014, (25-27 March 2014, Oxford, UK)

NGS 2014, (31 March-03 April 2014, Oxford, UK)


RNAi2012 Speakers

27 March 2012

Professor Kaz Taira
Title: Small RNAs and epigenetics
Professor, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba; The University of Tokyo; Tokyo University & Graduate School of Social Welfare; and Nagase & Co Ltd, Tokyo, Japan

Professor Dr Ben Berkhout (Keynote Presentation)
Director, Laboratory of Experimental Virology, Academic Medical Center, University of Amsterdam, The Netherlands
Title: Optimization of antiviral RNAi molecules: A Dicer-independent shRNA processing route

Professor Dr Albrecht Piiper
Professor, Department of Medicine, University of Frankfurt/M, Germany
Title: MicroRNAs in blood serum as non-invasive biomarkers in chronic hepatitis C

Dr Raymond Schiffelers 
Assistant Professor, UMC Utretch, The Netherlands
Title: Identification of microRNA based therapeutic candidates using a unique lentiviral microRNA overexpression library

Dr Lorena Di Lisio
Pathology Service, Hospital Universitario Marques de Valdecilla, and IFIMAV, Spain
Title: microRNAs in B-cell lymphomas

Dr Blanche Schroen
Assistant Professor, Center for Heart Failure Research, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, The Netherlands
Title: Role of microRNAs in ageing-associated cardiac remodeling

Dr Roy Edward
Biostatus Limited, Shepshed, LEICS, UK
Title: Red/far-red fluorescing DNA-specific anthraquinones for nucl:cyto segmentation and viability reporting in cell-based assays

28 March 2012

Professor Dr Paul Holvoet
Head of Atherosclerosis and Metabolism Unit, Department of Cardiovascular Diseases, Katholieke Universiteit Leuven, Belgium
Title: Interaction between oxidative stress and inflammation in obesity and atherosclerosis

Professor Dr Jens Brüning
Director, Department of Mouse Genetics and Metabolism,  Institute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, GermanyTitle: Role of miRNA expression in insulin resistance and type 2 diabetes

Professor Nagy Habib
Director, HPB Clinical Services, Imperial College Healthcare NHS Trust, GI Lead Clinician, and Department of Surgery & Cancer, Imperial College London, UK
Title: Stem cells in diabetes

Dr Trevor Dale (Sponsored by Sigma Life Sciences)
Professor/Deputy Research Division Leader, School of Biosciences, Cardiff University, Cardiff, UK
Title: Analysis of a Wnt signalling network using high throughput screening

Dr Stephen Brown (Sponsored by Molecular Devices)
Head, RNAi Facility, The University of Sheffield, UK
Title: Lights, camera, action. Genome-wide RNAi screens using automated microscopy

Dr Dmitry Samarsky
Executive Vice President, Technology and Business Development, RiboBio Co, China
Title: In vivo delivery of the oligonucleotide-based drugs

Technology Workshop by Molecular Devices

Technology Workshop by Sigma-Aldrich

Dr Mark Behlke
Chief Scientist, IDTDNA, USA
Title: Non-base modifiers for anti-miRNA and other antisense applications

Professor Adrian Harris (Keynote Presentation)
Director of Oncology, CRUK at the University of Oxford, UK
Title: Prognostic and mechanistic roles of miRNAs in human breast cancer

Professor Dr Achim Aigner
Professor, Rudolf-Boehm-Institute for Pharmacology and Toxicology Clinical Pharmacology, University of Leipzig, Germany
Title: RNAi-mediated knockdown of HER family members and RNAi double/triple knockdown strategies in ovarian cancer

Professor John Aplin
University of Manchester, Manchester, UK
Title: Short-interfering RNA mediated knock-down of integrin αvβ3or its ligand osteopontin suppresses embryo-epithelial adhesion at implantation

Dr Karen Forbes
School of Biomedicine, University of Manchester, Manchester, UK
Title: IGF regulates miR-483-3p expression in the developing human placenta via an IGF1R/ERK pathway

29 March 2012

Professor Andrew Miller
Professor, University College London, UK
Title: TBA

Dr Stephen Hart
Reader in Molecular Genetics, Wolfson Centre for Gene Therapy of Childhood Disease, UCL, UK
Title: Lipid-Peptide Nanocomplexes for the Targeted Delivery of siRNA

Dr Muriel Golzio
Group Leader, Institut de Pharmacologie et de Biologie Struscturale, Centre National de la Recherche Scientifique, France
Title: siRNA electrotransfer into cancer cells

Dr Tobias Restle
Professor, Institute of Molecular Medicine, Universität zu Lübeck, Germany
Title: Minimal mechanistic model of guide RNA dependent target RNA slicing by recombinant human Argonaute2 protein

Dr Sterghios Moschos
Reader in Industrial Biotechnology, University of Westminster, UK
Title: Oligonucleotide inhalation: The liver is the target

Dr Tobias Poehlmann
Institute of Macromolar Chemistry and Organic Chemistry, Friedrich-Schiller-University of Jena, Germany
Title: Development of peptide-blocked siRNA – a cell-specific toxin


RNAi2012 Posters

Identification of anti-angiogenic miRNA active in vitro and in vivo

Negar Babae, Meriem Bourajjaj, Afrouz Yousefi, Judy R van Beijnum, Maike van Berkel, Suzanna Vidic, Willemijn M Gommans, Francesco Cerisoli, Mark Verheul, Paula van Noort, Enrico Mastrobattista, Gert Storm, Raymond M Schiffelers, Arjan W Griffioen, Eugene Berezikov, Edwin Cuppen, Roel QJ Schaapveld, Gregoire P Prevost

Utrecht Institute for Pharmaceutical Sciences, Utrecht University, The Netherlands


Dennis B Bela-ong, Brian Dall Schyth, and Niels Lorenzen

Department of Poultry, Fish, and Fur Animals, National Veterinary Institute, Technical University of Denmark, Hangøvej 2, DK-8200 Århus N, DENMARK

Actual and Predicted Off-target Effects Induced By siRNAs Targeting the HPV16 E7 Oncogene Demonstrate No Correlation in Human Papillomavirus-negative Keratinocytes in vitro

Burrows JE, Saini HK, Murray MJ, van Dongen S, Davis M, Barker EM, Ward DM, Enright AJ, Pett MR, Coleman N

Department of Pathology, University of Cambridge, CB2 1QP, UK

Receptor-mediated uptake of oligonucleotide nanocomplexes with cell-penetrating peptides and their formulation into a pharmaceutically stable solid dosage form

Kariem Ezzat, Henrik Helmfors and Ülo Langel

Department of Neurochemistry, Stockholm University, 10691 Stockholm, Sweden

High Throughput analysis of neuronal polarity following RNAi mediated gene knockdown

Jamie Freeman , David Elliott, Antonella Riccio and Robin Ketteler

MRC LMCB, University College London, Gower Street, London, WC1E 6BT, United Kingdom

Analysis of Sina and Sinb genes in triticale (xTriticosecale Wittmack) by RNAi –mediated gene silencing

S Gasparis, W Orczyk, A Nadolska-Orczyk

Department of Plant Transformation and Cell Engineering, Plant Breeding and Acclimatization Institute, Radzikow, 05-870 Blonie, Poland

RIP2 Silencing Attenuates Allergic Airway Inflammation in Mice

Fera Y. Goh, Lin Chin Lah, Katrina LTP Cook, Nadine Upton, Lin Tao and W.S. Fred Wong

Departments of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore

SiRNA delivery by novel lipid based carriers targeted to microvascular endothelial cells

Jan AAM Kamps, Niek GJ Leus, Piotr S Kowalski, Henri ëtte WM Morselt, Eduard G Talman, Marcel HJ Ruiters, Grietje Molema

University Medical Center Groningen, Laboratory for Endothelial Biomedicine & Vascular Drug Targeting research, Hanzeplein 1, 9713 GZ Groningen, The Netherlands

MicroRNA 145 overexpression suppresses embryo-epithelial juxtacrine communication at implantation by modulating maternal IGF1R expression

Youn-Jung Kang, Karen Forbes and John D Aplin

Maternal and Fetal Health Research Group, University of Manchester, St Mary’s Hospital, Oxford Road, Manchester, M13 9WL, UK and Nuffield Department of Obstetrics & Gynaecology, University of Oxford, Level 3, Women’s Centre , John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK

Serum microRNA-122 as prognostic marker of survival in patients with liver cirrhosis

Oliver Waidmann, Verena Köberle, Friederike Brunner, Stefan Zeuzem, Bernd Kronenberger, Albrecht Piiper

Department of Medicine, University of Frankfurt/M., Theodor-Stern-Kai 7, 60590 Frankfurt, Germany


S Larashati, BD Schyth and N Lorenzen

Department of Poultry, Fish and Fur Animals, Veterinary Institute-Denmark Technical University, Århus N, Denmark

SiRNA mediated inhibition of tick-borne encephalitis virus in organotypic brain cultures infected with Langat virus

Carola Maffioli, Stephen L Leib and Olivier Engler

Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Switzerland

MICRORNA ANALYSIS OF exosomes isolated from human plasma

Alison T Merryweather-Clarke, Damian M Crawford, Adam J.Ritchie, David JP Ferguson, John Burthem and David J Roberts

Nuffield Department of Clinical Laboratory Sciences, University of Oxford, Oxford, United Kingdom

Development of tools for studying functions and interacting partners of human Argonaute proteins

Innarella M.R., Mescalchin A.

Institute of Molecular Medicine, University of Lübeck, Center for Structural and Cell Biology in Medicine (CSCM), Ratzeburger Allee 160, 23538 Lübeck, Germany

Allele-selective inhibition of huntingtin expression by single-stranded RNAs that act through the RNAi pathway

Hannah Pendergraff, Dongbo Yu, Thazha P. Prakash, Eric E. Swayze, Walt F. Lima, Stanley T. Crooke, Holly Kordasiewicz and David R. Corey

microRNA regulation in rainbow trout infected with a fish pathogenic rhabdovirus

Brian Dall Schyth, Seyed Amir Hossein Jalali, Lasse Boegelund Kristensen, Finn Skou Pedersen and Niels Lorenzen

Dept Poultry, Fish and Fur Animals, Technical University of Denmark, 8200 Aarhus N, Denmark

RNAi mediated cdk4 and cdk6 genes silencing as a potential approach for neuroprotection

Malgorzata Sierant, Danuta Piotrzkowska, Barbara Nawrot

Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Lodz 90-363, Sienkiewicza 112, Poland

Development of Nanocomplexes for Targeted siRNA Delivery

Aristides Tagalakis, Luisa Saraiva, Kenth Gustafsson and Stephen Hart

Wolfson Centre for Gene Therapy of Childhood Disease, UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK

Characterization of extracellular circulating microRNA

Turchinovich A, Weiz L, Langheinz A, Burwinkel B

Molecular EpidemiologyGerman Cancer Research CenterIm Neuenheimer Feld 58169120 Heidelberg, Germany

Serum microRNA-122 as prognostic marker of survival in patients with liver cirrhosis

Oliver Waidmann, Verena Köberle, Friederike Brunner, Stefan Zeuzem, Bernd Kronenberger, Albrecht Piiper

Department of Medicine I, University of Frankfurt/M., Theodor-Stern-Kai 7, 60590 Frankfurt, Germany

Disulfide based poly(amido amine) copolymers for siRNA delivery

A. Yousefi, P. Vader, L.J. van der Aa, J.F.J. Engbersen, G. Storm, Enrico, Mastrobattista, R.M. Schiffelers

Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht, University, P.O. Box 80082, 3508 TB Utrecht, The Netherlands

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