(Subject to change: The conference may finish slightly earlier or later than the advertised time)
Presentation language: English
Venue: The Jarvis Doctorow Hall, St Edmund Hall, Queen’s Lane, Oxford, UK
Time Zone: All times mentioned refer to British Standard/Summer Time (BST) – London/GMT+01:00.
Password and links: Registered conference delegates will be sent joining information and conference access links a few days before the conference.
World Time Converter: https://www.worldtimebuddy.com/
NB: Due to the hybrid nature of the agenda and the wide geographical locations of our speakers, it may not have always been possible to group together related presentations.
0830: Registration
0920: Welcome and housekeeping
0930: INSOAP updates
0950: Professor Maureen McKeague
Assistant Professor of Chemistry, Department of Chemistry & Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada
Exploring the chemical diversity of aptamer interactions
1010: Professor Philip Johnson
Professor of Chemistry, Department of Chemistry, York University, Toronto, Ontario, Canada
Structural and functional analysis of small molecule-aptamer interactions
1030: Dr Pietro Delcanale
Assistant Professor, Department of Mathematical, Physical and Computer Sciences, University of Parma, Parma, Emilia-Romagna, Italy
Fluorescence Correlation Spectroscopy for a quantitative characterization of aptamer interactions in complex solutions
1050: Professor Julian Tanner
Director, The Common Core and Assistant Dean and Associate Director, School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, ChinaThe University of Hong Kong
Symbiotic relationships at the interface of aptamers and nanostructures
1110: Refreshment break, posters and networking
1140: Professor Larry Gold (Keynote speaker)
University of Colorado and SomaLogic Inc, Boulder, CO, USA
Difficulties in drug discovery, independent of the nature of the therapeutic modality
1210: Dr Neboja Janjic
Chief Science Officer, SomaLogic Inc, Boulder, CO, USA
From single-stranded nucleic acid sequences to intricate shapes: emerging insights from aptamer structures
1230: Professor José Martins
Professor, Department of Organic and Macromolecular Chemistry, University of Gent, Krijgslaan, Gent, Belgium
NMR Impression of a structure switching testosterone binding aptamer
1250: Dr Gregory Penner
CEO, NeoVentures Biotechnology Inc, London, Ontario, Canada
Meta-analysis of predicted aptamer secondary structures
1310: Lunch and networking
1410: Professor Chun Kit Kwok
Professor, Department of Chemistry, The City University of Hong Kong, Kowloon, Hong Kong, PR China
Development, Characterization, and Application of G-quadruplex Targeting L-RNA Aptamers
1430: Miss Danyang Ji
Graduate Researcher, Department of Chemistry, The City University of Hong Kong, Kowloon, Hong Kong, PR China
Selective targeting of parallel G-quadruplex structure using L-RNA aptamer
1450: Professor Sarah Shigdar
Associate Professor, School of Medicine, Faculty of Health, Deakin University, Geelong, Australia
Developing a platform technology that crosses the blood brain barrier to deliver drugs to cancer cells in the brain
1510: Dr Gisela Lorente
Chief Scientific Officer, Aptadel Therapeutics, Parc Cientific Barcelona, Barcelona, Spain
Aptamers as a delivery tool for the treatment of childhood cancer
1530: Professor Dr Günter Mayer
Professor, University of Bonn, Life & Medical Sciences Institute (LIMES), Chemical Biology, Bonn, Germany
Chemokine inhibition by aptamers inhibit immune cell chemotaxis in vivo
1550: Dr Axel Vater
Chief Scientific Officer, Aptarion Biotech AG, Berlin, Germany
Advancing AON-D21: A complement C5a-neutralizing L-aptamer ready for trials in patient
1610: Refreshment break, posters and networking
1630: Dr Najeeb Khalid
Chief Scientific Officer, Two-Photon Research Inc, Montreal, QC, Canada
Aptamers Molecular Photonic Beacons enable emerging diagnostic platform for instant Point of Need medical testing and digital healthcare
1650: Professor Dr Beatrix Suess
Professor, Synthetic Genetic Circuits, Technical University of Darmstadt, Darmstadt, Germany
Next-level riboswitch development – Implementation of Capture-SELEX
allows fast and easy identification of new synthetic riboswitches
1710: Professor Donald Burke-Aguero (V)
Professor of Molecular microbiology and immunology, MU Bond Life Sciences Center, University of Missouri, Columbia, Missouri, USA
Anti-EGFR RNA aptamers target lung cancers harboring clinically relevant EGFR activating mutations
1730: Close of Day
1900: Networking dinner (by prior booking or invitation)
Professor Michael Przybylski (1948-2023)
CSO and Head, Centre for Analytical Biochemistry and Biomedical Mass Spectrometry, Rüsselsheim, Germany
DNA and RNA aptamer epitope determination by affinity-mass spectrometry opens new approaches for peptide biomarkers and molecular diagnostics
0900: Dr Sireethorn Tungsirisurp
Research Associate, Department of Analytical, Environmental and Forensic Sciences, Faculty of Life Sciences and Medicine, King’s College London, Waterloo Campus, London, UK
Development and characterisation of surface-binding and internalised DNA aptamers targeting cardiac fibroblasts
0920: Miss Leila Mohammadnejad
Graduate Researcher, Department of Thoracic Cardiac and Vascular Surgery, Clinical Research Laboratory, University Hospital Tübingen, Tübingen, Germany
A specific DNA Aptamer targeting extracellular matrix Fibronectin diminishes the adhesion and migration of A549 cancer cells
0940: Dr Shazana Hilda Shamsuddin
Lecturer, Biosensors & Bionanotechnology, Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan
Comparative analysis between DNA Aptamer-based and antibody-based detection against E6 oncoprotein of HPV16 in cervical cancer tissues
1000: Refreshment break, posters and networking
1030-1130: Flash-talks to be chaired by Professors McKeague and Shigdar
Giles (V), AlBorhani, Chao, Churcher, Costanzo, Dobrea, Drees, Feng, Ferreira, Girbas, Jonczyk, Jørgensen, Kaiyum, Le Dortz, Neis, Osborne, Patwari, Schellinck, Thavaseelan, Tungsirisurp
1130: Professor Ichiro Hirao
Chief Scientific Officer, Xenolis Pte Ltd, Singapore
ExSELEX for high-affinity six-letter DNA aptamer generation by genetic
alphabet expansion
1200: Dr Iwao Waga
Senior Fellow, NEC Solution Innovators, Ltd, CTO, FonesLife, and Director and Project Leader, Center of Innovation Project in Tohoku University, Sendai, Miyagi, Japan
Food-safety aptamers in an unobtrusive daily life sensing
1220: Lunch, posters and networking
1310: Mr Hamish Dunham
Graduate Researcher, School of Biological Sciences, Te Herenga Waka Victoria University of Wellington, Wellington, New Zealand
Developing a multiplex electrochemical aptamer-based biosensor for the quantification of free amino acids
1330: Dr Sondes Ben Aissa
Chemistry Department, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK
Development of an aptamer-based E-sensor for the real-time monitoring of cortisol
1350: Mr Tathagata Pal
Graduate Researcher, Biosensors & Bioinstrumentation Laboratory, Department of Bioscience & Bioengineering, Indian Institute of Technology Bombay, Mumbai, Maharashtra, India
Detection of arsenic in water by U-bent fiber optic Localized Surface Plasmon Resonance aptasensor
1410: Miss Magdalena Raykova
Graduate Researcher, Civil and Environmental department, University of Strathclyde, Glasgow, Scotland, UK
Electrochemical detection of ampicillin: comparison between an internal and an external redox reporter
1430: Discussion and Close
